Diagnosis of keratoconus with optical coherence tomography

Purpose The aim of the study was to assess the accuracy of optical coherence tomography (OCT) (3D OCT-2000) in diagnosing keratoconus by measuring the central corneal thickness and the central curvature radius. Patients and methods In this observational study, 50 patients with keratoconus underwent corneal topography, ultrasound pachymetry, Scheimpflug imaging, and anterior-segment optical coherence tomography (AS-OCT). Results The mean corneal power measured by AS-OCT was 51.65 ± 0.78 D, that measured with corneal topography was 50.19 ± 0.64 D, and that with the Sirius Scheimpflug camera was 50.78 ± 0.82 D. The mean central corneal thickness measured by OCT was 486 ± 73 μm, that measured by ultrasound was 475 ± 49 μm, and that using the Sirius Scheimpflug camera was 481 ± 66 μm. Conclusion 3D OCT-2000 may be a useful alternative for measuring the anterior corneal power and the central corneal thickness in keratoconic eyes.