Back to Search
Start Over
Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector
- Source :
- Cell, Cell, 2021, 184 (21), pp.5391-5404.e17. ⟨10.1016/j.cell.2021.09.009⟩
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- International audience; Plant immunity is activated upon pathogen perception and often affects growth and yield when it is constitutively active. How plants fine-tune immune homeostasis in their natural habitats remains elusive. Here, we discover a conserved immune suppression network in cereals that orchestrates immune homeostasis, centering on a Ca2+-sensor, RESISTANCE OF RICE TO DISEASES1 (ROD1). ROD1 promotes reactive oxygen species (ROS) scavenging by stimulating catalase activity, and its protein stability is regulated by ubiquitination. ROD1 disruption confers resistance to multiple pathogens, whereas a natural ROD1 allele prevalent in indica rice with agroecology-specific distribution enhances resistance without yield penalty. The fungal effector AvrPiz-t structurally mimics ROD1 and activates the same ROS-scavenging cascade to suppress host immunity and promote virulence. We thus reveal a molecular framework adopted by both host and pathogen that integrates Ca2+ sensing and ROS homeostasis to suppress plant immunity, suggesting a principle for breeding disease-resistant, high-yield crops.
- Subjects :
- pyriculariose du riz
F60 - Physiologie et biochimie végétale
Homéostasie
Plant Immunity
Virulence
Oryza sativa
Plant disease resistance
Xanthomonas oryzae
General Biochemistry, Genetics and Molecular Biology
Immune system
Maladie des plantes
Immunity
Effecteur moléculaire
H20 - Maladies des plantes
chemistry.chemical_classification
Reactive oxygen species
biology
Effector
Rhizoctonia solani
food and beverages
Résistance aux maladies
Catalase
dérivé réactif de l'oxygène
Cell biology
Physiologie végétale
[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy
chemistry
biology.protein
Immunité
Subjects
Details
- Language :
- English
- ISSN :
- 00928674 and 10974172
- Database :
- OpenAIRE
- Journal :
- Cell, Cell, 2021, 184 (21), pp.5391-5404.e17. ⟨10.1016/j.cell.2021.09.009⟩
- Accession number :
- edsair.doi.dedup.....eb2466b85cabb3653b9a768ba9d365a0