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Analogues of polyamine alkaloids and their synthetic advantages
- Source :
- Farmaco (Societa chimica italiana : 1989). 56(1-2)
- Publication Year :
- 2001
-
Abstract
- Several polyamine derivatives were synthesized in order to produce novel antagonists of muscular nicotinic acetylcholine receptors. Their affinities were compared with those of philanthotoxin PhTX-343.
- Subjects :
- medicine.drug_class
Stereochemistry
Pharmaceutical Science
Philanthotoxin
Carboxamide
macromolecular substances
Nicotinic Antagonists
Affinities
Spermidine
chemistry.chemical_compound
Structure-Activity Relationship
Nicotinic agonist
Biochemistry
chemistry
Drug Discovery
medicine
Polyamines
Structure–activity relationship
Animals
Humans
Polyamine
Acetylcholine receptor
Subjects
Details
- ISSN :
- 0014827X
- Volume :
- 56
- Issue :
- 1-2
- Database :
- OpenAIRE
- Journal :
- Farmaco (Societa chimica italiana : 1989)
- Accession number :
- edsair.doi.dedup.....eb1b32d1ddb1696181a1a5a547742f5c