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Evaluation of subclinical myocardial dysfunction using speckle tracking echocardiography in patients with radiographic and non-radiographic axial spondyloarthritis
- Source :
- European Journal of Rheumatology, Vol 7, Iss 1, Pp 9-15 (2020)
- Publication Year :
- 2020
- Publisher :
- AVES Yayincilik, 2020.
-
Abstract
- OBJECTIVE: To evaluate whether there is any difference between radiographic axial spondyloarthritis (r-axSpA), also termed ankylosing spondylitis (AS), and non-radiographic (nr-) axSpA, with respect to subclinial myocardial dysfunction using speckle tracking echocardiography (STE). METHODS: This was a cross-sectional case control study. We included 72 patients with AS, 38 patients with nr-axSpA, and 56 age-matched healthy subjects. Patients with cardiac disease and cardiac risk factors affecting STE were excluded. The disease burden evaluated by the BASDAI, BASFI, BAS-G, and ASAS-HI scores were comparable in both the r- and nr-axSpA groups. A detailed echocardiographic examination including the M-mode, Doppler, and STE was applied to whole study population. RESULTS: Duration of the disease, the use of an anti-TNFα agent, and CRP levels were higher in patients with AS. Although the AS, nr-axSpA, and control groups had similar ejection fraction values (59±5.2, 60±4.6, 60±4.6, respectively, and p=0.499), the global longitudinal peak systolic strain (GLS) (20.5±3.3, 21.1±3.5, and 22.3±2.4, respectively, and p
- Subjects :
- 030203 arthritis & rheumatology
lcsh:Immunologic diseases. Allergy
medicine.medical_specialty
Ankylosing spondylitis
Univariate analysis
Ejection fraction
business.industry
Case-control study
Speckle tracking echocardiography
030204 cardiovascular system & hematology
medicine.disease
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Cardiology
Original Article
BASFI
business
lcsh:RC581-607
BASDAI
Subclinical infection
Subjects
Details
- Language :
- English
- ISSN :
- 21484279 and 21479720
- Volume :
- 7
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- European Journal of Rheumatology
- Accession number :
- edsair.doi.dedup.....eb0836cfcd685a561d9c0b1cdc425bcf