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Non-opioid recreational drug use and a prolonged HIV outbreak among men who have sex with men in Taiwan: An incident case-control study, 2006-2015
- Source :
- Journal of the Formosan Medical Association, Vol 121, Iss 1, Pp 237-246 (2022)
- Publication Year :
- 2020
-
Abstract
- Background/purpose Limited data are available on the role of illicit non-injecting drug use in a prolonged HIV outbreak that predominantly affected men who have sex with men (MSM) in Taiwan since 2006. We aimed to assess associations between specific types of drug use and incident HIV infections in this outbreak. Methods We conducted a retrospective case–control study among MSM clients at voluntary counselling and testing (VCT) service at National Taiwan University Hospital (Taipei, Taiwan). We used BED IgG-capture enzyme immunoassay to identify incident HIV infection (cases), individually matched to HIV-negative MSM clients (controls) by HIV testing date. We used a structured questionnaire to obtain the information on illicit drug use and sexual risk behaviors. Results From a total of 15,305 MSM client visits during 2006–2015, 387 cases were matched to 1012 controls. Use of inhaled nitrites (adjusted odds ratio [aOR] 2.1), MDMA (aOR 2.9), amphetamines (aOR 1.6), and ketamine (aOR 1.5) were independently associated with incident HIV infection. Polydrug (≥2 drugs) use was associated with the highest risk (aOR 4.3; 95% CI 2.6–7.2). While the proportion of MSM VCT clients who reported use of any recreational drug remained stable during 2006–2015 (average: 9.7%, P: 0.38), there was a shift in specific types of drug use, from MDMA/ketamine to inhaled nitrites/amphetamine, after 2011 (all Ps Conclusion Non-opioid recreational drugs use is associated with incident HIV infection in this prolonged HIV outbreak. There is an urgent need to formulate an effective public health response to mitigate the risk.
- Subjects :
- Drug
Male
Medicine (General)
medicine.medical_specialty
Recreational Drug
media_common.quotation_subject
Taiwan
HIV Infections
Men who have sex with men
Disease Outbreaks
03 medical and health sciences
Sexual and Gender Minorities
R5-920
0302 clinical medicine
Environmental health
Recreational Drug Use
Medicine
Humans
Homosexuality, Male
BED IgG-capture enzyme immunoassay
media_common
Retrospective Studies
Voluntary counselling and testing
business.industry
Public health
Case-control study
HIV
virus diseases
Outbreak
General Medicine
Odds ratio
Recreational drug use
030220 oncology & carcinogenesis
Case-Control Studies
030211 gastroenterology & hepatology
business
Subjects
Details
- ISSN :
- 09296646
- Volume :
- 121
- Issue :
- 1 Pt 2
- Database :
- OpenAIRE
- Journal :
- Journal of the Formosan Medical Association = Taiwan yi zhi
- Accession number :
- edsair.doi.dedup.....ea4e9724202b0ee7970cc8d19fe2d415