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Adult Presentation of Noncirrhotic Portal Hypertension and Ascites following Treatment for Wilms’ Tumor in Childhood
- Source :
- Case Reports in Gastroenterology, Kievit, L, Kræmer, P, Hamilton-Dutoit, S & Grønbæk, H 2018, ' Adult Presentation of Noncirrhotic Portal Hypertension and Ascites following Treatment for Wilms' Tumor in Childhood ', Case Reports in Gastroenterology, vol. 12, no. 1, pp. 56-62 . https://doi.org/10.1159/000486389, Case Reports in Gastroenterology, Vol 12, Iss 1, Pp 56-62 (2018)
- Publication Year :
- 2018
- Publisher :
- S. Karger AG, 2018.
-
Abstract
- A 37-year-old male, who at the age of 8 years had been treated for right-sided Wilms’ tumor with nephrectomy, radiotherapy, and chemotherapy, presented with noncirrhotic portal hypertension (NCPH), grade 2 esophageal varices, and ascites. A CT scan demonstrated hypoplasia of liver segments 2 and 3. A liver biopsy showed portal tract fibrosis without cirrhosis, with histological features of NCPH. Liver vein catheterization showed a normal portal pressure gradient of 5 mm Hg while spleen to hepatic vein pressure was 29 mm Hg. NCPH after therapy for Wilms’ tumor is described in children within the first few years after treatment. This is the first case report in which the patient first presented symptoms as an adult, many years after cancer treatment.
- Subjects :
- medicine.medical_specialty
Cirrhosis
Portal venous pressure
Wilms’ tumor
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Esophageal varices
Case and Review
Internal medicine
Ascites
medicine
lcsh:RC799-869
Portal hypertension
Vein
medicine.diagnostic_test
business.industry
Wilms' tumor
medicine.disease
medicine.anatomical_structure
030220 oncology & carcinogenesis
Liver biopsy
lcsh:Diseases of the digestive system. Gastroenterology
030211 gastroenterology & hepatology
medicine.symptom
Noncirrhotic portal hypertension
business
Subjects
Details
- ISSN :
- 16620631
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Case Reports in Gastroenterology
- Accession number :
- edsair.doi.dedup.....ea40821b672297b905a1a43ac144ab5a