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Dyes for Eyes™: Hydrodynamics, Biocompatibility and Efficacy of ‘Heavy' (Dual) Dyes for Chromovitrectomy
- Source :
- Ophthalmologica. 230:51-58
- Publication Year :
- 2013
- Publisher :
- S. Karger AG, 2013.
-
Abstract
- As epiretinal membranes (ERMs), the internal limiting membrane (ILM) and the vitreous cortex are essentially transparent tissues, or translucent structures, nontraumatic removal may be challenging in various types of macular surgery. Vital dyes stain these thin tissues, thus allowing for better visualization of these structures during vitrectomy and selective ‘membrane peeling' from the underlying retina. To avoid swirling of the dye within the fluid-filled vitreous cavity, and to better target the dye onto the macula, a fluid-air exchange is commonly performed. However, this may jeopardize visualization of the macula during peeling due to clouding of the posterior lens capsule, and may lead to postoperative visual field defects. Recently, a new dye solution for staining the ERM and ILM simultaneously has been developed that circumvents the need for fluid-air exchange, i.e. MembraneBlue-Dual™. This paper will focus on the hydrodynamics and biocompatibility of this ‘heavy' dual dye and its efficacy for staining of the ILM and/or ERMs during posterior segment surgery in a multicenter clinical setting.
- Subjects :
- Male
medicine.medical_specialty
Materials science
genetic structures
Biocompatibility
Cell Survival
medicine.medical_treatment
Vitrectomy
Retinal Pigment Epithelium
Stain
Basement Membrane
Cell Line
Polyethylene Glycols
Cohort Studies
chemistry.chemical_compound
Materials Testing
Rosaniline Dyes
medicine
Humans
Coloring Agents
Aged
Viscosity
Epiretinal Membrane
Trypan Blue
General Medicine
medicine.disease
eye diseases
Sensory Systems
Staining
Surgery
Posterior segment of eyeball
Drug Combinations
Ophthalmology
chemistry
Vitreous membrane
Hydrodynamics
Female
Trypan blue
sense organs
Epiretinal membrane
Biomedical engineering
Subjects
Details
- ISSN :
- 14230267 and 00303755
- Volume :
- 230
- Database :
- OpenAIRE
- Journal :
- Ophthalmologica
- Accession number :
- edsair.doi.dedup.....ea24a0364b123b18a76ca4ed7732bdcd