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Itch and Ache on Dialysis: New Approaches to Manage Uremic Pruritus and Restless Legs
- Source :
- Blood Purification. 49:222-227
- Publication Year :
- 2019
- Publisher :
- S. Karger AG, 2019.
-
Abstract
- Background: Uremic pruritus (UP) and restless legs syndrome (RLS) are highly prevalent complaints among patients with end-stage renal disease (ESRD) undergoing chronic dialysis. These chronic troublesome symptoms lead to a significant decrease in quality of life (QOL) and increase in mortality rate. Despite their distressing characteristics, these symptoms usually remain under-recognized by healthcare providers. Therefore, careful history intake, and stepwise treatment are essential. Numerous pharmacological and non-pharmacological treatments have been demonstrated to help in controlling these 2 conditions. Summary: In this review, we discuss the latest findings regarding UP and RLS among ESRD patients on maintenance dialysis. We also examine different treatment options in this group of patients. The majority of these patients do not have the opportunity to receive a kidney transplant and need other treatments for these burdensome symptoms in order to improve their QOL and prognosis. Key Messages: UP and RLS are common but underdiagnosed conditions in ESRD patients on maintenance dialysis that are related to a decline in patients’ QOL and poor prognosis. The pathophysiology of these conditions remains not well understood. Therefore, controversies still exist on treatment options. Treating these conditions provides an opportunity to improve the health-related QOL and outcomes of dialysis patients.
- Subjects :
- medicine.medical_specialty
Uremic pruritus
medicine.medical_treatment
030232 urology & nephrology
Pain
Disease
030204 cardiovascular system & hematology
End stage renal disease
03 medical and health sciences
0302 clinical medicine
Quality of life
Renal Dialysis
Restless Legs Syndrome
medicine
Humans
Pain Management
Restless legs syndrome
Intensive care medicine
Dialysis
business.industry
Pruritus
Mortality rate
Hematology
General Medicine
medicine.disease
Nephrology
Chronic dialysis
Quality of Life
Kidney Failure, Chronic
business
Subjects
Details
- ISSN :
- 14219735 and 02535068
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Blood Purification
- Accession number :
- edsair.doi.dedup.....e9efe0be7939590e225a956c2e51784d