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Ultrasound-Guided Focused Ultrasound Treatment for Painful Bone Metastases: A Pilot Study
- Source :
- Ultrasound in medicinebiology. 46(6)
- Publication Year :
- 2019
-
Abstract
- Focused ultrasound (FUS) for palliation of bone metastases has typically been performed under magnetic resonance guidance. To address limitations of this approach, this pilot study evaluated a stand-alone, portable FUS device guided by diagnostic ultrasound alone (ultrasound [US]-guided FUS). Nine patients were treated; safety and efficacy were assessed for 10 d after the procedure, and medical charts were evaluated to assess durability of pain response. The procedure was safe and tolerable, with four patients reporting minor skin-related irritations. Average pain score decreased from 6.9 at baseline to 3.2 at day 10; analgesic use on average also decreased from baseline to day 10. Six patients had durable pain relief as assessed after the follow-up period. Our study provides evidence that US-guided FUS is a safe, tolerable and versatile procedure. It appears to be effective in achieving durable pain response in patients with painful bone metastases. Further research is required to refine the technology and optimize its efficacy.
- Subjects :
- Adult
Male
medicine.medical_specialty
Acoustics and Ultrasonics
medicine.medical_treatment
Analgesic
Biophysics
Pain relief
Bone Neoplasms
Pilot Projects
Focused ultrasound
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Pain Management
Radiology, Nuclear Medicine and imaging
Aged
Aged, 80 and over
Radiological and Ultrasound Technology
medicine.diagnostic_test
business.industry
Ultrasound
Palliative Care
Magnetic resonance imaging
Cancer Pain
Middle Aged
High-intensity focused ultrasound
Ultrasound guided
Tolerability
030220 oncology & carcinogenesis
Quality of Life
High-Intensity Focused Ultrasound Ablation
Female
Radiology
business
Subjects
Details
- ISSN :
- 1879291X
- Volume :
- 46
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Ultrasound in medicinebiology
- Accession number :
- edsair.doi.dedup.....e9c805c247319b02c2aff6621e045f76