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Role of WUSCHEL in Regulating Stem Cell Fate in the Arabidopsis Shoot Meristem
- Source :
- Cell. 95(6):805-815
- Publication Year :
- 1998
- Publisher :
- Elsevier BV, 1998.
-
Abstract
- The shoot meristem gives rise to the aerial parts of higher plants by continuously initiating new organs. The basis of this activity is its ability to maintain a pool of pluripotent stem cells, which are the ultimate source of all tissues of the shoot. In Arabidopsis plants mutant for the WUSCHEL (WUS) gene, the stem cells are misspecified and appear to undergo differentiation. Here, we show that WUS encodes a novel homeodomain protein which presumably acts as a transcriptional regulator. The pattern of WUS expression suggests that stem cells in the shoot meristem are specified by an underlying cell group which is established in the 16-cell embryo and becomes localized to its prospective domain of function by asymmetric cell divisions.
- Subjects :
- Plant stem cell
DNA, Plant
Meristem
Molecular Sequence Data
Arabidopsis
Biology
Genes, Plant
General Biochemistry, Genetics and Molecular Biology
Gene Expression Regulation, Plant
Botany
Point Mutation
Amino Acid Sequence
Cloning, Molecular
Plant Proteins
Homeodomain Proteins
Base Sequence
Arabidopsis Proteins
Biochemistry, Genetics and Molecular Biology(all)
fungi
Chromosome Mapping
Gene Expression Regulation, Developmental
food and beverages
Cell Differentiation
Meristem maintenance
biology.organism_classification
Cell biology
ABC model of flower development
Meristem initiation
Floral meristem determinacy
Stem cell
Subjects
Details
- ISSN :
- 00928674
- Volume :
- 95
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Cell
- Accession number :
- edsair.doi.dedup.....e996efa80ce73089e02ff743cedd4961
- Full Text :
- https://doi.org/10.1016/s0092-8674(00)81703-1