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Impedance Spectroscopic Investigation of the Bilayer Lipid Membranes Formed from the Phosphatidylserine–Ceramide Mixture
- Source :
- Journal of Membrane Biology. 227:67-75
- Publication Year :
- 2009
- Publisher :
- Springer Science and Business Media LLC, 2009.
-
Abstract
- Electrochemical impedance spectroscopy was used for the study of two-component lipid membranes. Phosphatidylserine and ceramide were to be investigated because they play an important biochemical role in cell membranes. The research on biolipid interaction was focused on a quantitative description of processes that take part in a bilayer. Assumed models of interaction between amphiphilic molecules and the equilibria that take place there were described by mathematical equations for the studied system. The possibility of complex formation for a two-component system forming bilayers was assumed, which could explain the deviation from the additivity rule. The molecular area and the equilibrium constant of the complex were determined.
- Subjects :
- Ceramide
Physiology
Bilayer
Lipid Bilayers
Biophysics
Analytical chemistry
Biological membrane
Phosphatidylserines
Cell Biology
Lipid bilayer mechanics
Model lipid bilayer
Ceramides
Models, Biological
chemistry.chemical_compound
Membrane
chemistry
Electric Impedance
Electrochemistry
Lipid bilayer phase behavior
Lipid bilayer
Subjects
Details
- ISSN :
- 14321424 and 00222631
- Volume :
- 227
- Database :
- OpenAIRE
- Journal :
- Journal of Membrane Biology
- Accession number :
- edsair.doi.dedup.....e9533466c2e544748b9a3ad4b21fc4d5