Effect of variation in ovine WFIKKN2 on growth traits appears to be gender-dependent

WFIKKN2 may play a role in the regulation of muscle growth and development, but to date there have been no reports on the effect of variation in WFIKKN2 on growth and carcass traits in livestock. In this study, the effect of variation in ovine WFIKKN2 was investigated in 800 New Zealand Romney lambs (395 male and 405 female), with five previously described variants (A to E) being identified. Variation in ovine WFIKKN2 was not found to affect various growth traits in the female lambs, but the presence of variant B was associated (P B was associated (P WFIKKN2 may have a differential effect on growth in male and female lambs and hence that the gene may be expressed in, or act in, a gender-specific fashion.