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Indications for frontolateral laryngectomy and prognostic factors of failure
- Source :
- European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 256(8)
- Publication Year :
- 1999
-
Abstract
- The aim of this study was a retrospective analysis of the oncological results in a group of patients treated by frontolateral laryngectomy using clinical and histopathological correlations in order to review the indications for surgery. In all, 150 patients underwent frontolateral laryngectomy as described by Leroux-Robert. All were staged according to the 1992 UICC TNM classification. Factors examined were clinical T, histopathological T, tumor infiltration of the anterior commissure and the vocal cord muscle, survival without disease and the percentage of local relapses. Twenty-one patients had local relapses (14%), while four patients developed second primary tumors (2.7%). Among the different correlations examined, microscopic infiltration of the anterior commissure was related to a greater number of local relapses (25.5% vs 5%) and a 55% survival with with no evidence of disease (NED). The crude 5-year NED survival was 66% and was influenced by second primary tumors and metastases (7.4%) and non-oncological diseases (14.6%). These data show the need for a re-evaluation of the indications for frontolateral laryngectomy because subtotal reconstructive laryngectomy could be performed more safely in the more advanced cases. In contrast, cases with more limited tumors might be better treated by laser for a more functional and cost-beneficial result.
- Subjects :
- Adult
Male
medicine.medical_specialty
Cord
medicine.medical_treatment
Anterior commissure
Laryngectomy
Postoperative Complications
medicine
Retrospective analysis
Humans
Laryngeal Neoplasms
Aged
Retrospective Studies
Laryngoscopy
business.industry
General Medicine
Second primary cancer
Middle Aged
Prognosis
Surgery
Survival Rate
Otorhinolaryngology
Head and neck surgery
Carcinoma, Squamous Cell
Female
Neurosurgery
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 09374477
- Volume :
- 256
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
- Accession number :
- edsair.doi.dedup.....e8b91e58f765c1a2affe9608271a6ee9