Back to Search
Start Over
Re-examining ferritin-bound iron: current and developing clinical tools
- Source :
- Clinical Chemistry and Laboratory Medicine (CCLM). 59:459-471
- Publication Year :
- 2020
- Publisher :
- Walter de Gruyter GmbH, 2020.
-
Abstract
- Iron is a highly important metal ion cofactor within the human body, necessary for haemoglobin synthesis, and required by a wide range of enzymes for essential metabolic processes. Iron deficiency and overload both pose significant health concerns and are relatively common world-wide health hazards. Effective measurement of total iron stores is a primary tool for both identifying abnormal iron levels and tracking changes in clinical settings. Population based data is also essential for tracking nutritional trends. This review article provides an overview of the strengths and limitations associated with current techniques for diagnosing iron status, which sets a basis to discuss the potential of a new serum marker – ferritin-bound iron – and the improvement it could offer to iron assessment.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Iron
Clinical Biochemistry
Clinical settings
030204 cardiovascular system & hematology
Body iron
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Intensive care medicine
Anemia, Iron-Deficiency
biology
business.industry
Iron levels
Biochemistry (medical)
Iron Deficiencies
General Medicine
Iron deficiency
medicine.disease
Review article
Ferritin
030104 developmental biology
Population based data
Ferritins
biology.protein
Iron status
business
Biomarkers
Subjects
Details
- ISSN :
- 14374331 and 14346621
- Volume :
- 59
- Database :
- OpenAIRE
- Journal :
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Accession number :
- edsair.doi.dedup.....e87d9e64d37144feb82c44bd7b5adcd9
- Full Text :
- https://doi.org/10.1515/cclm-2020-1095