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Synthetic (polymer) biology (membrane): functionalization of polymer scaffolds for membrane proteins

Authors :
James C. S. Ho
Zhaolong Hu
Madhavan Nallani
Source :
Current opinion in biotechnology. 46
Publication Year :
2016

Abstract

A plethora of polymer-based scaffolds have been designed to facilitate biochemical and biophysical investigation of membrane proteins, with a common goal to stabilize and present them in a functional format. In this review, an up-to-date account of such polymer-based supports and incorporation methodologies are presented. Furthermore, conceptual and imminent technological advances, with associated technical challenges are proposed.

Details

ISSN :
18790429
Volume :
46
Database :
OpenAIRE
Journal :
Current opinion in biotechnology
Accession number :
edsair.doi.dedup.....e81d761eb58a0c080981c9702f133909