Synthesis of Prenylarenes and Related (Multisubstituted Allyl)arenes from Aryl Halides and Homoallyl Alcohols via Palladium-Catalyzed Retro-Allylation

Authors :: Koichiro Oshima
Masayuki Iwasaki
Hideki Yorimitsu
Source :: BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN. 82(2):249-253
Publication Year :: 2009
Publisher :: CHEMICAL SOC JAPAN, 2009.
Abstract: The reactions of aryl halides with 2,3,3-trimethyl-4-penten-2-ol in the presence of a palladium catalyst result in prenyl transfer from the alcohol to aryl halides via retro-allylation, yielding prenylarenes. Other multisubstituted allyl groups such as the 2,3-dimethyl-2-butenyl group are introduced to aromatic rings.

Subjects :: chemistry.chemical_compound
chemistry
Aryl
Halide
Organic chemistry
chemistry.chemical_element
Alcohol
Aromaticity
General Chemistry
Medicinal chemistry
Palladium catalyst
Palladium
Catalysis

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