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The six-minute walk test in patients with AL amyloidosis: a single centre case series
- Source :
- British Journal of Haematology. 177:388-394
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- Summary The six-minute walk test (6MWT) has been widely used as an objective evaluation of functional exercise capacity and response to medical intervention in cardiopulmonary diseases. However, little is known about the 6MWT in evaluating patients with AL amyloidosis. We performed a retrospective study of 120 adults with systemic AL amyloidosis (60 with cardiac involvement and 60 without cardiac involvement) who had their initial evaluation at the Amyloidosis Center between 2013 and 2015 and had undergone 6MWT as a measure of functional exercise capacity. Forty-seven patients with cardiac involvement and 41 patients without cardiac involvement were included in the final analysis. The six-minute walk distances (6MWD) were 368 ± 105 m and 420 ± 116 m (mean ± SD), respectively (P = 0·03). Among AL amyloidosis patients with cardiac involvement, the 6MWD was associated with New York Heart Association class (P
- Subjects :
- Male
medicine.medical_specialty
New York Heart Association Class
medicine.drug_class
Walk Test
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Natriuretic peptide
AL amyloidosis
Humans
Aged
Retrospective Studies
Cardiopulmonary disease
Exercise Tolerance
business.industry
Amyloidosis
Hazard ratio
Retrospective cohort study
Hematology
Middle Aged
medicine.disease
030220 oncology & carcinogenesis
Heart failure
Cardiology
Female
Cardiomyopathies
business
Subjects
Details
- ISSN :
- 00071048
- Volume :
- 177
- Database :
- OpenAIRE
- Journal :
- British Journal of Haematology
- Accession number :
- edsair.doi.dedup.....e77233e6c8201e07b06e9765eec3a9b9