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Sonotubometry: a useful tool to measure intra-individual changes in eustachian tube ventilatory function
- Source :
- Archives of Otolaryngology--Head & Neck Surgery, 133, 763-6, Archives of Otolaryngology--Head & Neck Surgery, 133, 8, pp. 763-6
- Publication Year :
- 2007
-
Abstract
- Contains fulltext : 53292.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To determine whether intra-individual changes in eustachian tube (ET) function induced by local application of a histamine phosphate solution can be detected using an improved sonotubometer. DESIGN: The function of the ET was measured with a revised sonotubometer before and after histamine was applied to the nasopharyngeal ostium of the ET. SETTING: Tertiary referral hospital. PATIENTS: Twenty-five otologically healthy adults. INTERVENTIONS: A histamine phosphate solution with a concentration of 16 mg/mL was applied to the nasopharyngeal ostium of the ET using a pressure nebulizer. MAIN OUTCOME MEASURES: The number of openings during 10 acts of swallowing. This outcome value could range from 0 to 10. The number of ET openings before and after histamine application was compared. RESULTS: The mean number of ET openings dropped dramatically: from 8.4 before application of histamine to 2.7 after application. This difference was statistically significant; there was a mean difference of 5.6 (95% confidence interval, 4.4-6.9; P < .001). CONCLUSION: Sonotubometry is capable of detecting intra-individual changes in ET function and may therefore be a very useful tool in monitoring and/or clinical research of ET dysfunction or function.
- Subjects :
- Adult
Male
Age-related aspects of cancer [ONCOL 2]
Eustachian tube
chemistry.chemical_compound
Histamine Agents
Swallowing
Interventional oncology [UMCN 1.5]
Perception and Action [DCN 1]
medicine
Humans
Neurosensory disorders [UMCN 3.3]
business.industry
Eustachian Tube
General Medicine
Middle Aged
Intra individual
Confidence interval
Deglutition
Human Reproduction [NCEBP 12]
Ostium
Nebulizer
Sound
medicine.anatomical_structure
Acoustic Stimulation
Otorhinolaryngology
chemistry
Evaluation of complex medical interventions [NCEBP 2]
Anesthesia
Female
Surgery
Sonotubometry
business
Functional Neurogenomics [DCN 2]
Histamine
Subjects
Details
- ISSN :
- 08864470
- Volume :
- 133
- Database :
- OpenAIRE
- Journal :
- Archives of Otolaryngology--Head & Neck Surgery
- Accession number :
- edsair.doi.dedup.....e74856bb3be84308a19e0eabe8800455