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Emergence of Zika virus infection in China
- Source :
- PLoS Neglected Tropical Diseases, PLoS Neglected Tropical Diseases, Vol 14, Iss 5, p e0008300 (2020)
- Publication Year :
- 2020
- Publisher :
- Public Library of Science, 2020.
-
Abstract
- Currently, Zika virus (ZIKV) is spreading across the world and no ZIKV infection cases have ever been reported in China. Here, we aimed to determine whether ZIKV infection exists in China. Blood samples of 273 healthy individuals were collected from Nanning City, Guangxi Province, China in March 2019. We found that 9.5% (26/273) and 1.8% (5/273) of healthy persons were positive to ZIKV total antibody (IgG and/or IgM) IgM antibody, respectively. All ZIKV positive plasma samples were negative to Dengue virus and West Nile virus. Among the ZIKV antibody positive plasma samples, 65.4% (17/26) exhibited neutralizing activity to ZIKV. Followed up studies showed that none had clinical symptoms of ZIKV infection and oversea experience. Together, our study indicates that endemic ZIKV infections emerge in China, which not only suggested that ZIKV posed a potential threat to public health in China, but also expand the ZIKV epidemic areas in East and Southeast Asia.<br />Author summary ZIKA, caused by mosquito-borne Zika virus (ZIKV), is typically asymptomatic or with mild fever, and the occurrence of ZIKV infections are reported around the world. However, limited ZIKV epidemiological investigation was performed and no ZIKV infection cases were ever reported in China. Here, we observed that Zika virus also distributes in China. This work not only suggests ZIKV as a potential threat to public health in China but also expands our knowledge of ZIKV epidemic regions in East and Southeast Asia. Therefore, government officials, physicians and public health workers in China need to pay attention to ZIKV infection cases.
- Subjects :
- RNA viruses
Male
Igm antibody
Physiology
RC955-962
Dengue virus
medicine.disease_cause
Pathology and Laboratory Medicine
Antibodies, Viral
Biochemistry
Zika virus
Southeast asia
Geographical Locations
Seroepidemiologic Studies
Arctic medicine. Tropical medicine
Immune Physiology
Medicine and Health Sciences
Medicine
Enzyme-Linked Immunoassays
Immune System Proteins
biology
Plasma samples
Zika Virus Infection
Middle Aged
Body Fluids
Infectious Diseases
Blood
Medical Microbiology
Viral Pathogens
Viruses
Female
Public aspects of medicine
RA1-1270
Antibody
Pathogens
Anatomy
West Nile virus
Research Article
Neglected Tropical Diseases
Adult
China
Asia
Immunology
Research and Analysis Methods
Microbiology
Blood Plasma
Antibodies
Young Adult
Humans
Immunoassays
Microbial Pathogens
Biology and life sciences
Flaviviruses
business.industry
Public Health, Environmental and Occupational Health
Organisms
Proteins
Zika Virus
biology.organism_classification
Tropical Diseases
Zika Fever
Virology
Antibodies, Neutralizing
Immunoglobulin M
Immunoglobulin G
People and Places
biology.protein
Immunologic Techniques
business
Subjects
Details
- Language :
- English
- ISSN :
- 19352735 and 19352727
- Volume :
- 14
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- PLoS Neglected Tropical Diseases
- Accession number :
- edsair.doi.dedup.....e6ebe24c2d60c6dabffc6e16b623b2f0