The impact of atrial mechanical function on <scp>age‐dependent</scp> presentation of neurocardiogenic syncope

Background The contribution of atrial and ventricular function in neurocardiogenic syncope (NCS) pathophysiology is elusive. Hypothesis We assessed the influence of echocardiographic properties to the age of presentation and NCS recurrences. Methods We assigned 124 patients with symptoms suggesting NCS, to those with syncope initiation at age 35 years (group B, n = 68). Echocardiographic indices were measured before head‐up tilt test (HUTT). Results A total of 55 had positive HUTT (44%) with a trend favoring group A (p = .08). Group A exhibited lower left atrial (LA) volume index (17 &#177; 6 vs. 22 &#177; 11 ml/m2, p = .015), higher LA ejection fraction (69 &#177; 10 vs. 63 &#177; 11%, p = .008), LA peak strain (reservoir phase 41 &#177; 13 vs. 31 &#177; 14%, p = .001, contraction phase 27 &#177; 11 vs. 15 &#177; 10%, p 3 recurrences (82.0% vs. 50.1%, p