Coexistence of hypertrophic osteoarthropathy and myelofibrosis

Hypertrophic osteoarthropathy (HOA) is a condition characterized by arthralgia/arthritis, clubbing, and periosteal reaction. Primary form of HOA is observed at early ages of life and is hereditary in nature. Secondary HOA is more frequently seen in clinical setting and occurs as a result of various disorders including inflammatory and malignant diseases. Regression in HOA may be seen after the treatment of underlying condition. In this report, we presented a case of HOA coexisted with myelofibrosis and reviewed the current literature. © 2014 Elsevier Editora Ltda. All rights reserved. Coexistencia de osteoartropatia hipertrofica e mielofibrose