No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression

Authors :: Alessandro Serretti
Carlos Forray
Julien Mendlewicz
Raffaella Calati
Lenore Snyder
Diana De Ronchi
M. Fink
Isabelle Massat
Daniel Souery
Siegfried Kasper
Alberto Chiesa
Yves Lecrubier
Joseph Bollen
Sylvie Linotte
Joseph Zohar
Irina Antonijevic
Serretti, A
Chiesa, A
Calati, R
Massat, I
Linotte, S
Kasper, S
Lecrubier, Y
Fink, M
Antonijevic, I
Forray, C
Snyder, L
Bollen, J
Zohar, J
De Ronchi, D
Souery, D
Mendlewicz, J
Serretti A.
Chiesa A.
Calati R.
Massat I.
Linotte S.
Kasper S.
Lecrubier Y.
Fink M.
Antonijevic I.
Forray C.
Snyder L.
Bollen J.
Zohar J.
De Ronchi D.
Souery D.
Mendlewicz J.
Source :: Psychiatry Research. 188:166-169
Publication Year :: 2011
Publisher :: Elsevier BV, 2011.
Abstract: In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations. © 2010 Elsevier Ltd.

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