ESR1 inhibits ionizing radiation-induced ferroptosis in breast cancer cells via the NEDD4L/CD71 pathway

Authors :: Lin Liu
Chen Zhang
Shugen Qu
Rui Liu
Huajian Chen
Zhenzhen Liang
Zhujun Tian
Lan Li
Shumei Ma
Xiaodong Liu
Source :: Archives of biochemistry and biophysics. 725
Publication Year :: 2022
Abstract: Ferroptosis is the name given to the type of non-apoptotic cell death that is caused by iron accumulation and subsequent lipid peroxidation. However, how ionizing radiation (IR)-induced ferroptosis is regulated in estrogen receptor-positive (ER

Subjects :: Antigens, CD
Nedd4 Ubiquitin Protein Ligases
Radiation, Ionizing
Receptors, Transferrin
Biophysics
Estrogen Receptor alpha
MCF-7 Cells
Ferroptosis
Humans
Breast Neoplasms
Female
Molecular Biology
Biochemistry

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