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Guided bone regeneration in staged vertical and horizontal bone augmentation using platelet-rich fibrin associated with bone grafts: a retrospective clinical study
- Source :
- International Journal of Implant Dentistry, Vol 6, Iss 1, Pp 1-10 (2020), International Journal of Implant Dentistry
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- Background The use of guided bone regeneration (GBR) for vertical and horizontal bone gain is a predictable approach to correct the bone defects before implant installation; however, the use of different protocols is associated with different clinical results. It is suggested that platelet-rich fibrin (PRF) could improve the outcomes of regenerative procedures. Thus, this study aimed to describe the bone gain associated with GBR procedures combining membranes, bone grafts, and PRF for vertical and horizontal bone augmentation. Materials and methods Eighteen patients who needed vertical or horizontal bone regeneration before installing dental implants were included in the study. The horizontal bone defects were treated with a GBR protocol that includes the use of a mixture of particulate autogenous and xenogenous grafts in the proportion of 1:1, injectable form of PRF (i-PRF) to agglutinate the graft, an absorbable collagen membrane covering the regenerated region, and leukocyte PRF (L-PRF) membrane covering the GBR membrane. The vertical bone defects were treated with the same grafted mixture protected by a titanium-reinforced non-resorbable high-density polytetrafluoroethylene (d-PTFE-Ti) membrane and covered by L-PRF. The bone gain was measured using a cone-beam computed tomography at baseline and after a period of 7.5 (± 1.0) months. Results All patients underwent surgery to install implants after this regenerative protocol. The GBR produces an increase in bone thickness (p < 0.001) and height (p < 0.005) after treatment, with a bone gain of 5.9 ± 2.4 for horizontal defects and 5.6 ± 2.6 for vertical defects. In horizontal defects, the gain was higher in the maxilla than in mandible (p = 0.014) and in anterior than the posterior region (p = 0.033). No differences related to GBR location were observed in vertical defects (p > 0.05). Conclusion GBR associated with a mixture of particulate autogenous and xenogenous grafts and i-PRF is effective for vertical and horizontal bone augmentation in maxillary and mandibular regions, permitting sufficient bone gain to future implant placement. Trial registration REBEC, RBR-3CSG3J. Date of registration—19 July 2019, retrospectively registered. http://www.ensaiosclinicos.gov.br/rg/RBR-3csg3j/
- Subjects :
- Guided bone regeneration
Bone thickness
lcsh:Medicine
Dentistry
02 engineering and technology
Fibrin
Retrospective data
Bone augmentation
03 medical and health sciences
0302 clinical medicine
Medicine
Alveolar ridge augmentation
Bone regeneration
biology
business.industry
Research
Dental implants
lcsh:R
Platelet-rich fibrin
030206 dentistry
Alveolar Ridge Augmentation
021001 nanoscience & nanotechnology
lcsh:RK1-715
lcsh:Dentistry
biology.protein
Implant
i-PRF
0210 nano-technology
business
Alveolar bone grafting
Subjects
Details
- ISSN :
- 21984034
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- International Journal of Implant Dentistry
- Accession number :
- edsair.doi.dedup.....e662aa4796b5e170428fba5aa559ad77