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Radiofrequency-ablation of unresectable primary and secondary liver tumors: results in 88 patients
- Source :
- Langenbeck's Archives of Surgery. 391:118-123
- Publication Year :
- 2006
- Publisher :
- Springer Science and Business Media LLC, 2006.
-
Abstract
- Radiofrequency-ablation (RFA) is increasingly used for destruction of unresectable primary and secondary liver tumors. We report our experience in the use of RFA for the management of unresectable hepatic malignancies. Between February 2000 and December 2004 we have undertaken 120 RFA procedures to ablate 426 unresectable primary or metastatic liver tumors in 88 patients. RFA was performed via laparotomy (n=68), laparoscopy (n=9) or a percutaneous approach (n=43). Primary liver cancer was treated in seven patients (8%) and metastatic liver tumors were treated in 81 patients (92%). All patients were followed to assess complications, treatment response and recurrence of malignant disease. Procedure-related complication rate was low (3.4%). During a mean follow-up of 21.2 months, 15 patients had local tumor progression (17%), 21 patients (23,9%) had new malignant disease and 27 patients (30.7%) died from intervention-unrelated complications of their malignant disease. Additional liver lesions were identified in 27 (35%) of 77 cases by intraoperative ultrasound. Thirty-six patients received simultaneous resection and RFA. RFA is a safe, well-tolerated and effective treatment for patients with unresectable primary and secondary liver malignancies.
- Subjects :
- Adult
Male
medicine.medical_specialty
Liver tumor
Radiofrequency ablation
medicine.medical_treatment
law.invention
law
Laparotomy
medicine
Humans
Laparoscopy
Aged
medicine.diagnostic_test
business.industry
Liver Neoplasms
Middle Aged
Vascular surgery
medicine.disease
Survival Analysis
Cardiac surgery
Treatment Outcome
surgical procedures, operative
Cardiothoracic surgery
Catheter Ablation
Female
Surgery
Radiology
business
Abdominal surgery
Subjects
Details
- ISSN :
- 14352451 and 14352443
- Volume :
- 391
- Database :
- OpenAIRE
- Journal :
- Langenbeck's Archives of Surgery
- Accession number :
- edsair.doi.dedup.....e64deed4d32ae5ad55db40b75028466a