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Etiology of Pediatric Bacterial Meningitis Pre- and Post-PCV13 Introduction Among Children Under 5 Years Old in Lomé, Togo

Authors :
Joseph Nsiari-Muzeyi Biey
Mawussi Godonou
Abdul Karim Sesay
Novissi Tsogbale
Martin Antonio
Leopold D. Tientcheu
Bernard Ntsama
Peter Sylvanus Ndow
Dadja Essoya Landoh
Segla D. Tigossou
Madikay Senghore
Archibald Worwui
Brenda Kwambana-Adams
Yawo Dzayissè Atakouma
Djatougbe Ayaovi Elie Akolly
Rowan E Bancroft
Jason M. Mwenda
Anoumou Dagnra
Enyonam Tsolenyanu
M Fiawoo
Source :
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Publication Year :
2019
Publisher :
Oxford University Press (OUP), 2019.

Abstract

Background Pediatric bacterial meningitis (PBM) causes severe morbidity and mortality within Togo. Thus, as a member of the World Health Organization coordinated Invasive Bacterial Vaccine Preventable Diseases network, Togo conducts surveillance targeting Streptococcus pneumoniae (pneumococcus), Neisseria meningitidis (meningococcus), and Haemophilus influenzae, at a sentinel hospital within the capital city, Lomé, in the southernmost Maritime region. Methods Cerebrospinal fluid was collected from children<br />Streptococcus pneumoniae was the predominant pathogen responsible for pediatric bacterial meningitis during longitudinal sentinel surveillance within Togo, from 2010 to 2016. However, pneumococcal meningitis cases decreased by 88.1% (52/59) postvaccine introduction; from 59 cases prevaccine introduction to 7 cases postvaccine introduction.

Details

ISSN :
15376591 and 10584838
Volume :
69
Database :
OpenAIRE
Journal :
Clinical Infectious Diseases
Accession number :
edsair.doi.dedup.....e639ef5a85a66e3db45ea083920241f2