Moderating effects of sleep duration on diabetes risk among cancer survivors: analysis of the National Health Interview Survey in the USA

Azizi A Seixas,1,2 Lloyd Gyamfi,1 Valerie Newsome,1 Gabrielle Ranger-Murdock,1 Mark Butler,1 Diana Margot Rosenthal,1 Ferdinand Zizi,1 Irini Youssef,3 Samy I McFarlane,3 Girardin Jean-Louis1,2 1Center for Healthful Behavior Change, Department of Population Health, NYU Langone Health, 2Department of Psychiatry, NYU Langone Health, New York, NY, USA; 3Division of Endocrinology, Department of Medicine, State University of New York (SUNY), Downstate Medical Center, Brooklyn, NY, USA Background: Growing evidence suggests that cancer and diabetes may share common risk factors such as age, race/ethnicity, obesity, insulin resistance, sedentary lifestyle, smoking, and alcohol consumption. However, little is known about how habitual sleep duration (a known cardiometabolic risk factor) may affect the relationship between cancer and diabetes. The aim of this study was to investigate whether sleep duration moderated the relationship between history of cancer and diabetes. Methods: Data were extracted from the National Health Interview Survey dataset from 2004 to 2013 containing demographics, chronic diseases, and sleep duration (N=236,406). Data were analyzed to assess the moderating effect of short and long sleep durations on cancer and diabetes mellitus. Results: Our findings indicate that short sleep (odds ratio [OR] =1.07, 95% CI =1.03–1.11, P