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Brain perfusion imaging in neonates
- Source :
- NeuroImage: Clinical, Vol 31, Iss, Pp 102756-(2021), NeuroImage : Clinical
- Publication Year :
- 2021
- Publisher :
- Elsevier, 2021.
-
Abstract
- Graphical abstract<br />Highlights • MRI is the modality of choice to image and quantify cerebral perfusion. • Imaging of neonatal brain perfusion is possible using MRI and ultrasound. • Novel ultrafast ultrasound imaging allows for excellent spatiotemporal resolution. • Understanding cerebral hemodynamic changes of neonatal adaptation is key.<br />Abnormal variations of the neonatal brain perfusion can result in long-term neurodevelopmental consequences and cerebral perfusion imaging can play an important role in diagnostic and therapeutic decision-making. To identify at-risk situations, perfusion imaging of the neonatal brain must accurately evaluate both regional and global perfusion. To date, neonatal cerebral perfusion assessment remains challenging. The available modalities such as magnetic resonance imaging (MRI), ultrasound imaging, computed tomography (CT), near-infrared spectroscopy or nuclear imaging have multiple compromises and limitations. Several promising methods are being developed to achieve better diagnostic accuracy and higher robustness, in particular using advanced MRI and ultrasound techniques. The objective of this state-of-the-art review is to analyze the methodology and challenges of neonatal brain perfusion imaging, to describe the currently available modalities, and to outline future perspectives.
- Subjects :
- NIRS, Near-Infrared Spectroscopy
IV, Intravenous
Perfusion scanning
Review Article
PET, Positron Emission Tomography
Pediatrics
UUI, Ultrafast Ultrasound Imaging
T1w, T1-weighted imaging
SNR, Signal-To-Noise Ratio
HIE, Hypoxic-Ischemic Encephalopathy
IVIM, Intravoxel Incoherent Motion
medicine.diagnostic_test
Ultrasound
EEG, Electroencephalogram
Brain
CT, Computed Tomography
Magnetic Resonance Imaging
Ultrasound techniques
Perfusion
Neurology
SPECT, Single Photon Emission Computed Tomography
Radiology
MRI
medicine.medical_specialty
Perfusion Imaging
Cognitive Neuroscience
Computer applications to medicine. Medical informatics
R858-859.7
MRI, Magnetic Resonance Imaging
CBF, Cerebral Blood Flow
medicine
Neonatal brain
Humans
Radiology, Nuclear Medicine and imaging
CBV, Cerebral Blood Volume
Cerebral perfusion pressure
RC346-429
ComputingMethodologies_COMPUTERGRAPHICS
Modalities
business.industry
Infant, Newborn
T2w, T2-weighted imaging
Magnetic resonance imaging
CEUS, Contrast Enhanced Ultrasound
FDG, 2-Deoxy-2[18F]-Fluoro-D-Glucose
HD, High-Density
ASL, Arterial Spin Labelling
RI, Resistivity Index
Neurology (clinical)
Neurology. Diseases of the nervous system
Tomography, X-Ray Computed
business
T2*, gradient echo T2 weighted imaging
Subjects
Details
- Language :
- English
- ISSN :
- 22131582
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- NeuroImage: Clinical
- Accession number :
- edsair.doi.dedup.....e5fc3dc738dee7451153445e0825d0c4