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Less severe retinopathy of prematurity induced by surfactant replacement therapy
- Source :
- Acta paediatrica (Oslo, Norway : 1992). 85(12)
- Publication Year :
- 1996
-
Abstract
- To assess the effect of surfactant replacement therapy (SRT) on the prevalence and severity of retinopathy of prematurity (ROP), we compared data from 160 SRT-treated preterm infants with data from 230 historic controls. The prevalence of ROP was 30.6% in the treatment group and 23.4% in the control group. Severe ROP (stages 3-4) was seen in 6.1% of the infants with ROP in the treatment group and 20.3% of the ROP patients in the control group. Surfactant therapy had no influence on the prevalence of ROP (odds ratio 1.4, 95% confidence interval 0.797--2.459, p = 0.242). However, SRT was associated with a decreased risk for severe ROP, compared to mild ROP (odds ratio 0.226, 95% confidence interval 0.056-0.905, p = 0.036). These data suggest that SRT is associated with a decreased risk for severe ROP.
- Subjects :
- congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
genetic structures
Eye disease
Surfactant therapy
Gastroenterology
Internal medicine
medicine
Humans
Retinopathy of Prematurity
Retrospective Studies
Respiratory distress
business.industry
Respiratory disease
Infant, Newborn
Retinopathy of prematurity
Pulmonary Surfactants
General Medicine
Odds ratio
medicine.disease
eye diseases
Confidence interval
Surgery
Pediatrics, Perinatology and Child Health
sense organs
business
human activities
Retinopathy
Subjects
Details
- ISSN :
- 08035253
- Volume :
- 85
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Acta paediatrica (Oslo, Norway : 1992)
- Accession number :
- edsair.doi.dedup.....e5b6e163e45d99d286b40dc423e69a05