A bromine analogue of picoplatin: a new substance from the group of platinum-based chemotherapeutics

A new substance,cis-amminedibromido(2-methylpyridine-κN)platinum(II),cis-[PtBr2(C6H7N)(NH3)], which is a potential platinum-based antineoplastic agent for the treatment of patients with solid tumors, has been synthesized and structurally characterized. There is one molecule in the asymmetric unit and molecules are linkedviatwo symmetry-independent N—H...Br hydrogen bonds into zigzag chains running parallel to thecaxis. C—H...Br hydrogen bonds crosslink these chains to give a layer parallel to (010). N—H...Br hydrogen bonds and π–π stacking interactions between pairs of pyridine rings stack the layers alongb.