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Cardiac factors affecting the success of vardenafil in erectile dysfunction
- Source :
- Volume: 45, Issue: 4 751-757, Turkish Journal of Medical Sciences
- Publication Year :
- 2015
- Publisher :
- TÜBİTAK, 2015.
-
Abstract
- Background/aim: To evaluate the predictability of vardenafil success in patients with erectile dysfunction (ED) by using cardiological tests. Materials and methods: Patients diagnosed with ED who did not benefit from lifestyle changes (n = 68) were evaluated with an abridged 5-item version of the International Index of Erectile Function (IIEF-5). The pretreatment and posttreatment IIEF-5 scores were compared with pretreatment data obtained from cardiological examinations. Results: When pretreatment scores were compared with test parameters, mitral flow E/A ratio and tissue Doppler imaging (TDI) E?/A?, exercise test duration, exercise capacity in MET, and percentage of maximum heart rate were found to be statistically significant. Furthermore, there was a significant negative correlation between mitral flow E/A ratio, TDI E?/A?, exercise test duration, exercise capacity in MET, and the difference in post- and pretreatment IIEF-5 scores. Conclusion: As a diastolic function indicator, TDI E?/A? positively correlates with pretreatment IIEF-5 scores and negatively correlates with the beneficial effect of vardenafil treatment. As a result, the cardiological status of the patient correlates with individual IIEF-5 scores, and it seems to be useful in predicting vardenafil success.
- Subjects :
- Male
medicine.medical_specialty
Phosphodiesterase Inhibitors
Statistics as Topic
Biological Availability
Significant negative correlation
Doppler echocardiography
Doppler imaging
Cardiovascular System
Piperazines
Erectile Dysfunction
Vardenafil Dihydrochloride
Heart Rate
Predictive Value of Tests
Internal medicine
Heart rate
medicine
Humans
In patient
Sulfones
medicine.diagnostic_test
business.industry
Triazines
Penile Erection
Imidazoles
General Medicine
Middle Aged
Erectile dysfunction,phosphodiesterase type 5 inhibitor,diastolic dysfunction
medicine.disease
Echocardiography, Doppler
Surgery
Erectile dysfunction
Treatment Outcome
Vardenafil
Predictive value of tests
Cardiology
Drug Monitoring
business
medicine.drug
Subjects
Details
- Language :
- Turkish
- ISSN :
- 13000144 and 13036165
- Database :
- OpenAIRE
- Journal :
- Volume: 45, Issue: 4 751-757, Turkish Journal of Medical Sciences
- Accession number :
- edsair.doi.dedup.....e4d771340f499dadfae9ab3c0f624962