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Auditory Discrimination After Left-Hemisphere Stroke
- Source :
- Stroke. 34:1746-1751
- Publication Year :
- 2003
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2003.
-
Abstract
- Background and Purpose— We sought to determine the recovery of cortical auditory discrimination in aphasic, left-hemisphere-stroke patients by using an electrophysiological response called mismatch negativity (MMN) and speech-comprehension tests. Methods— MMN in 8 left-hemisphere stroke patients was recorded in response to duration and frequency changes in a repetitive, harmonically rich tone 4 and 10 days and again 3 and 6 months after their first unilateral stroke. Eight age-matched, healthy persons served as control subjects. Results— At 4 days after stroke onset, patients’ sound discrimination was impaired in their left hemisphere, as suggested by attenuated MMNs, especially to right-ear stimuli. At 3 months after stroke, however, MMN to the right-ear duration change had significantly increased and was of normal size. A significant change for the frequency MMN was found for left-ear stimuli between 3 and 6 months after stroke. During the follow-up period, progressive improvement in speech-comprehension tests was also observed. Furthermore, there was a significant correlation between the change in the duration MMN amplitude and the Boston Diagnostic Aphasia Examination speech-comprehension test from 10 days to 3 months after stroke. Conclusions— These results suggest that the MMN can be used as an index of the recovery of auditory discrimination.
- Subjects :
- Adult
Male
medicine.medical_specialty
Mismatch negativity
Electroencephalography
Audiology
behavioral disciplines and activities
Functional Laterality
050105 experimental psychology
Lateralization of brain function
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Reference Values
Communication disorder
Aphasia
Reaction Time
medicine
Humans
0501 psychology and cognitive sciences
Evoked Potentials
Stroke
Advanced and Specialized Nursing
medicine.diagnostic_test
business.industry
Sensory memory
05 social sciences
Recovery of Function
Middle Aged
medicine.disease
Surgery
Electrophysiology
Acoustic Stimulation
Laterality
Speech Discrimination Tests
Female
Neurology (clinical)
medicine.symptom
Tomography, X-Ray Computed
Cardiology and Cardiovascular Medicine
business
psychological phenomena and processes
030217 neurology & neurosurgery
Follow-Up Studies
Subjects
Details
- ISSN :
- 15244628 and 00392499
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Stroke
- Accession number :
- edsair.doi.dedup.....e4b4659f6d28d945bf8c2643ead4c47b