Could intradermal be an economical alternative route of administration for Japanese encephalitis vaccines?

Highlight Uptake of Japanese encephalitis (JE) vaccine remains low among travellers, with cost of vaccines likely being one of the main hurdles. We found that smaller doses of JE vaccine administered via intradermal (ID) had similar effect on seroconversion than standard doses administered via subcutaneous. ID is a cheaper yet effective route of JE vaccine administration, and could potentially increase vaccination uptake among travellers.