Back to Search
Start Over
COVID-19 and ECMO: the interplay between coagulation and inflammation—a narrative review
- Source :
- Critical Care, Critical care, 24(1):205, Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
- Publication Year :
- 2020
- Publisher :
- BioMed Central, 2020.
-
Abstract
- Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has presently become a rapidly spreading and devastating global pandemic. Veno-venous extracorporeal membrane oxygenation (V-V ECMO) may serve as life-saving rescue therapy for refractory respiratory failure in the setting of acute respiratory compromise such as that induced by SARS-CoV-2. While still little is known on the true efficacy of ECMO in this setting, the natural resemblance of seasonal influenza’s characteristics with respect to acute onset, initial symptoms, and some complications prompt to ECMO implantation in most severe, pulmonary decompensated patients. The present review summarizes the evidence on ECMO management of severe ARDS in light of recent COVID-19 pandemic, at the same time focusing on differences and similarities between SARS-CoV-2 and ECMO in terms of hematological and inflammatory interplay when these two settings merge.
- Subjects :
- PNEUMONIA
medicine.medical_specialty
ARDS
INTERLEUKIN-6
CANNULAE
medicine.medical_treatment
RESPIRATORY-FAILURE
Pneumonia, Viral
Review
030204 cardiovascular system & hematology
PRESSURE
Critical Care and Intensive Care Medicine
Severe Acute Respiratory Syndrome
Sepsis
EXTRACORPOREAL MEMBRANE-OXYGENATION
03 medical and health sciences
Betacoronavirus
0302 clinical medicine
Extracorporeal Membrane Oxygenation
Pandemic
Extracorporeal membrane oxygenation
Medicine
030212 general & internal medicine
Intensive care medicine
Blood Coagulation
Pandemics
FLOW PROPERTIES
Mechanical ventilation
SEPSIS
business.industry
SARS-CoV-2
lcsh:Medical emergencies. Critical care. Intensive care. First aid
COVID-19
lcsh:RC86-88.9
medicine.disease
Thrombocytopenia
MECHANICAL VENTILATION
Cytokine release syndrome
SEVERITY
surgical procedures, operative
Respiratory failure
CYTOKINE STORM
business
Cytokine storm
Coronavirus Infections
Cytokine Release Syndrome
LYMPHOPENIA
Subjects
Details
- Language :
- English
- ISSN :
- 1466609X and 13648535
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Critical Care
- Accession number :
- edsair.doi.dedup.....e463ce293d4f77cc2de2910859a383c7