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Direct Measurement of Ionization Charges in Single-phase Liquid Xenon Compton Telescope for 3γ Medical Imaging
- Source :
- 2019 IEEE Nuclear Science Symposium (NSS) and Medical Imaging Conference (MIC), 2019 IEEE Nuclear Science Symposium (NSS) and Medical Imaging Conference (MIC), Oct 2019, Manchester, United Kingdom. pp.1-4, ⟨10.1109/NSS/MIC42101.2019.9059808⟩, 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Oct 2019, Manchester, United Kingdom. ⟨10.1109/NSS/MIC42101.2019.9059808⟩
- Publication Year :
- 2019
- Publisher :
- IEEE, 2019.
-
Abstract
- International audience; We report the study of direct measurement of ionization charges in an innovative liquid xenon Compton camera of small animal imaging, named XEMIS2. It was combined with a novel 3γ medical imaging modality, showing a "TOF-like" PET performance, targeted to reduce the administered activity diametrically while preserving the image quality in oncology diagnosis. For the Compton cones reconstruction, the sequential low energy electronic recoils from Compton scattering of third γray (∼ 1 MeV) are measured directly from ionization signals under a high electric field of 2 kV/cm. The Geant4/NEST simulations studies reveal that the intrinsic energy and spatial resolutions of charges carriers measuring in liquid xenon are dominated respectively by the electron-ion recombination and the abstruse trajectory of recoil electrons. Besides, a novel ASIC front-end electronic, XTRACT, and data acquisition chain were developed, dedicated to optimizing the accuracy and efficiency of ionization signals measurement in XEMIS2. It allows a continuous read-out with ultra-low charges threshold and negligible deadtime per individual channel. The performing characteristics were calibrated in the prototype XEMIS1 under the XEMIS2 operation condition, showing a good homogeneous charge linearity response. Meanwhile, the data processing and analysis were developed, where the charge measurement has been optimized through Monte Carlo simulations. I. INTRODUCTION T HE personalized medicine as the heart of healthcare priorities of the 21 st century requires molecular imag-Manuscript
- Subjects :
- Ionization
Xenon
Charge measurement
Compton telescope
Monte Carlo method
chemistry.chemical_element
Electron
01 natural sciences
Imaging
03 medical and health sciences
0302 clinical medicine
Recoil
Electric field
0103 physical sciences
[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]
Pollution measurement
[PHYS]Physics [physics]
Physics
010308 nuclear & particles physics
Compton scattering
Data acquisition
Liquids
3. Good health
Computational physics
chemistry
030220 oncology & carcinogenesis
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
- Accession number :
- edsair.doi.dedup.....e4124995f8e9d6e094b74caedb1fa793