Synthesis and biological activity of chloroethyl pyrimidine nucleosides

Authors :: Vincent Chaleix
Michel Kraemer
Amel Hadj‐Bouazza
Odile Sainte Catherine
Rachida Zerrouki
Karine Teste
Ludovic Colombeau
Laboratoire de Chimie des Substances Naturelles (LCSN)
Université de Limoges (UNILIM)-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)
Chimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques (CSPBAT)
Université Paris 13 (UP13)-Institut Galilée-Université Sorbonne Paris Cité (USPC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Source :: Nucleosides, Nucleotides and Nucleic Acids, Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis, 2008, 27 (2), pp.110-20. ⟨10.1080/15257770701795813⟩, Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis, 2008, 27 (2), pp.110-120. ⟨10.1080/15257770701795813⟩
Publication Year :: 2008
Publisher :: HAL CCSD, 2008.
Abstract: International audience; The synthesis and biological activity of chloroethyl pyrimidine nucleosides is presented. One of these new nucleosides analogues significantly inhibited cell proliferation, migration and invasion as tested in vitro on the A431 vulvar epidermal carcinoma cell line.

Language :: English
ISSN :: 15257770 and 15322335
Database :: OpenAIRE
Journal :: Nucleosides, Nucleotides and Nucleic Acids, Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis, 2008, 27 (2), pp.110-20. ⟨10.1080/15257770701795813⟩, Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis, 2008, 27 (2), pp.110-120. ⟨10.1080/15257770701795813⟩
Accession number :: edsair.doi.dedup.....e3fcdb7fe006fc4607b5412a0d3ca534

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