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One-pot one-step deracemization of amines using ω-transaminases

Authors :
Giyoung Shin
Byung-Gee Kim
Minsu Shon
Hyungdon Yun
Sam Mathew
Source :
Chemical communications (Cambridge, England). 49(77)
Publication Year :
2013

Abstract

In this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. Using this method, various aromatic amines were successfully converted to their (R)-forms (>99%) with good conversion.

Subjects

Subjects :
Bacteria
Chemistry
Metals and Alloys
Enantioselective synthesis
Neosartorya
One-Step
Stereoisomerism
General Chemistry
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Mycobacterium
Comamonadaceae
Phenethylamines
Materials Chemistry
Ceramics and Composites
Organic chemistry
Transaminases
Vibrio

Details

ISSN :
1364548X
Volume :
49
Issue :
77
Database :
OpenAIRE
Journal :
Chemical communications (Cambridge, England)
Accession number :
edsair.doi.dedup.....e3f0af97b79984d10ee026f3f419ced3

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Authors Abstract Subjects Details