Orirubenones A, B and C, novel hyaluronan-degradation inhibitors from the mushroom Tricholoma orirubens

Authors :: Shintaro Inoue
Yumiko Tonomura
Hiroyuki Yoshida
Hirokazu Kawagishi
Shingo Sakai
Source :: Tetrahedron. 60:7049-7052
Publication Year :: 2004
Publisher :: Elsevier BV, 2004.
Abstract: Three new compounds, orirubenone A (1), B (2) and C (3) were isolated from the mushroom Tricholoma orirubens. Their structures were determined by spectral analyses. These compounds inhibited hyaluronan-degradation by human skin fibroblasts.

Subjects :: Mushroom
integumentary system
biology
Stereochemistry
Chemistry
Organic Chemistry
Hyaluronan degradation
Human skin
Tricholoma orirubens
General Medicine
biology.organism_classification
Biochemistry
Drug Discovery

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