Back to Search
Start Over
Lymph-node metastasis following total laryngectomy and total pharyngolaryngectomy for laryngeal and hypopharyngeal squamous cell carcinoma: Frequency, distribution and risk factors
- Source :
- European Annals of Otorhinolaryngology, Head and Neck Diseases, European Annals of Otorhinolaryngology, Head and Neck Diseases, Elsevier Masson, 2018, 135 (3), pp.163-166. ⟨10.1016/j.anorl.2017.11.008⟩
- Publication Year :
- 2018
- Publisher :
- HAL CCSD, 2018.
-
Abstract
- Objectives: To evaluate the prevalence and distribution of lymph-node metastasis after total laryngectomy or total pharyngolaryngectomy. Material and methods: Retrospective single-center series of 136 successive patients undergoing total laryngectomy or total pharyngolaryngectomy with neck dissection for squamous cell carcinoma of the larynx or hypopharynx. Results: The primary site was laryngeal in 110 cases and hypopharyngeal in 26. In 63 patients, surgery was first-line treatment; 73 were operated on for recurrence. The lymph-node metastasis rate, confirmed on histology, was 44.8% regardless of primary site. Hypopharyngeal location was a risk factor for lymph node metastasis (73.1%, P = 0.002) as was the supraglottic subsite (64.3%, P = 0.039). Levels Ha and III were invaded in 28.7% and 25.7% of cases, respectively. Level VIb lymph-node involvement was 23.8% in patients who underwent level VIb neck dissection. Lymph-node recurrence rate was 10.3% in levels II to IV and 13.2% in VIb. Conclusions: Whatever the tumor site, levels Ha and III were most frequently invaded. The high rate of histological involvement of level VIb and of recurrence argues for systematic elective bilateral neck dissection of these territories in some primary sites. (C) 2017 Elsevier Masson SAS. All rights reserved.
- Subjects :
- Larynx
Adult
Male
medicine.medical_specialty
medicine.medical_treatment
[SDV]Life Sciences [q-bio]
Laryngectomy
Lymph node metastasis
Metastasis
03 medical and health sciences
0302 clinical medicine
Pharyngectomy
Risk Factors
medicine
Humans
Risk factor
030223 otorhinolaryngology
Laryngeal Neoplasms
Aged
Retrospective Studies
Aged, 80 and over
Hypopharyngeal Neoplasms
business.industry
Squamous Cell Carcinoma of Head and Neck
Neck dissection
Histology
Middle Aged
medicine.disease
Total pharyngolaryngectomy
3. Good health
Surgery
[SDV] Life Sciences [q-bio]
medicine.anatomical_structure
Otorhinolaryngology
030220 oncology & carcinogenesis
Lymphatic Metastasis
Female
Neoplasm Recurrence, Local
business
Neck
Subjects
Details
- Language :
- English
- ISSN :
- 18797296 and 1879730X
- Database :
- OpenAIRE
- Journal :
- European Annals of Otorhinolaryngology, Head and Neck Diseases, European Annals of Otorhinolaryngology, Head and Neck Diseases, Elsevier Masson, 2018, 135 (3), pp.163-166. ⟨10.1016/j.anorl.2017.11.008⟩
- Accession number :
- edsair.doi.dedup.....e3ad70050e225c6f5250debf471982de