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Impact of 2 different aerobic periodization training protocols on left ventricular function in patients with stable coronary artery disease: an exploratory study
- Source :
- Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 46(5)
- Publication Year :
- 2020
-
Abstract
- We compared the impacts of linear (LP) and nonlinear (NLP) aerobic training periodizations on left ventricular (LV) function and geometry in coronary artery disease (CAD) patients. Thirty-nine CAD patients were randomized to either a 3-month isoenergetic supervised LP or NLP. All underwent standard echocardiography with assessment of 3D LV ejection fraction (LVEF), diastolic function, strain (global longitudinal, radial, and circumferential), and strain rate at baseline and study end. Training was performed 3 times/week and included high-intensity interval and moderate-intensity continuous training sessions. Training load was progressively increased in the LP group, while it was deeply increased and intercepted with a recovery week each fourth week in the NLP group. For the 34 analyzed patients, we found similar improvements for 3D LVEF (effect size (ES): LP, 0.29; NLP, 0.77), radial strain (ES: LP, 0.58; NLP, 0.48), and radial strain rate (ES: LP, 0.87; NLP, 0.17) in both groups (time for all: p ≤ 0.01). All other parameters of cardiac function remained similar. In conclusion, NLP and LP led to similar improvements in 3D LVEF and radial strain, suggesting a favourable positive cardiac remodelling through myofibers reorganization. These findings must be investigated in patients with more severe cardiac dysfunction. The study was registered on ClinicalTrials.gov (NCT03443193). Novelty: Linear and nonlinear periodization programs improved radial strain, accompanied by improvement of ejection fraction. Both aerobic periodization programs did not negatively impact cardiac function in coronary artery disease patients.
- Subjects :
- Cardiac function curve
Male
medicine.medical_specialty
Physiology
Endocrinology, Diabetes and Metabolism
CAD
Coronary Artery Disease
030204 cardiovascular system & hematology
High-Intensity Interval Training
Ventricular Function, Left
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Imaging, Three-Dimensional
Physiology (medical)
Internal medicine
medicine
Aerobic exercise
Humans
In patient
030212 general & internal medicine
Prospective Studies
Aged
Nutrition and Dietetics
Ventricular function
business.industry
General Medicine
Middle Aged
medicine.disease
Coronary heart disease
Exercise Therapy
Echocardiography
Sports periodization
Cardiology
Ventricular Function, Right
Female
business
Physical Conditioning, Human
Subjects
Details
- ISSN :
- 17155320
- Volume :
- 46
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
- Accession number :
- edsair.doi.dedup.....e390ccf29b07037b5d8f22b8b9f6e4e2