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Immunity to hepatitis A virus among working professionals in Poland - Results of a 3-year serological survey 2013-2015
- Source :
- Annals of Agricultural and Environmental Medicine, Vol 25, Iss 3, Pp 572-575 (2018)
- Publication Year :
- 2018
-
Abstract
- Introduction Hepatitis A (HA) is caused by infection with the hepatitis A virus (HAV). The differential etiological diagnosis of acute hepatitis is based on a positive result of the serological test detecting IgM class anti-HAV. For epidemiological studies on past infection and seroprevalence of HAV in populations, the tests measuring IgG class anti-HAV or total anti-HAV are used. Since the 1990s, specific prophylaxis is possible by vaccination against HA. In Poland, vaccination is recommended and in majority is performed at own cost. Material and methods Database was obtained from electronic medical records of the 2 major private health care providers networks (Luxmed and Medicover) operating in Poland. During a 3-year period (2013-2015), 1,124 persons with unknown status of anti-HA vaccination were tested for the presence of total anti-HAV. Objective. The aim of the study was to evaluate the seroprevalence of anti-HAV among working professionals in Poland. Results Anti-HAV were detected in 603 (53.6%) persons, while 521 (46.3%) tested negative. The study group was divided into 2 subgroups: 25-44 and 45-64-years-old. For detailed statistical analysis, the presence of anti-HAV was considered as a dependent variable, and its predictors were gender, age and the year of the test performance. The presence of anti-HAV was significantly more prevalent in older age group. The lack of specific antibodies was more prevalent in younger age group. Conclusions Results of the study show increasing susceptibility to HAV infection in the younger age group, compared with the older age group of corporate professional employees in large cities in Poland. Since the epidemiological situation of HA is currently changing with increasing number of symptomatic cases of HA, it is suggested that employers might consider including an additional procedure of vaccination against HA into their private health insurance portfolio.
- Subjects :
- Adult
Male
medicine.medical_specialty
viruses
vaccination against hepatitis type A
Antibodies, Viral
Serology
lcsh:Agriculture
03 medical and health sciences
Young Adult
0302 clinical medicine
Sex Factors
Risk Factors
Seroepidemiologic Studies
Surveys and Questionnaires
Epidemiology
Health care
Medicine
Seroprevalence
Humans
030212 general & internal medicine
Waste Management and Disposal
Ecology, Evolution, Behavior and Systematics
lcsh:Environmental sciences
lcsh:GE1-350
030505 public health
business.industry
Medical record
Public Health, Environmental and Occupational Health
lcsh:S
Age Factors
Hepatitis A
Middle Aged
medicine.disease
hepatitis A antibodies seroprevalence
Vaccination
Immunoglobulin G
Etiology
Female
Hepatitis A virus
Poland
0305 other medical science
business
Demography
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Annals of Agricultural and Environmental Medicine, Vol 25, Iss 3, Pp 572-575 (2018)
- Accession number :
- edsair.doi.dedup.....e368ebe2bc5e8c631aae87e941880c0e