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Effects of Ethanol Lock Therapy on Central Line Infections and Mechanical Problems in Children With Intestinal Failure
- Source :
- Journal of Parenteral and Enteral Nutrition. 41:625-631
- Publication Year :
- 2016
- Publisher :
- Wiley, 2016.
-
Abstract
- Objectives: Although use of 70% ethanol lock therapy (ELT) has been shown to decrease the rate of catheter-related bloodstream infections (CRBSIs) in patients with intestinal failure and central venous catheters (CVCs), concerns have been raised about its association with higher rates of mechanical problems and CVC replacements (CVC-Rs). We sought to compare the rates of CRBSI, mechanical problems, and CVC-Rs in a cohort of pediatric patients with intestinal failure, with and without ELT (ELT+ and ELT−, respectively). Methods: Data were collected in a retrospective chart review from February 2007 to May 2014. Mann-Whitney and Wilcoxon signed-rank tests were used to compare nonparametric and paired data, respectively. Results: Twenty-nine children had 9033 catheter days (CDs). The ELT+ group (vs ELT−) had lower rate of infection and significantly fewer CVC-Rs due to infection but significantly more mechanical events and related CVC-Rs with significantly shorter mean CVC survival. In 13 children who had a p...
- Subjects :
- 0301 basic medicine
Parenteral Nutrition
medicine.medical_specialty
Adolescent
Medicine (miscellaneous)
Clinical nutrition
03 medical and health sciences
0302 clinical medicine
Intestinal failure
Internal medicine
medicine
Central Venous Catheters
Humans
Ethanol lock
Intestinal Mucosa
Child
Retrospective Studies
Central line
030109 nutrition & dietetics
Nutrition and Dietetics
Ethanol
business.industry
Infant
Retrospective cohort study
equipment and supplies
Surgery
Intestines
Intestinal Diseases
Catheter
Parenteral nutrition
Catheter-Related Infections
Child, Preschool
Cohort
030211 gastroenterology & hepatology
business
Subjects
Details
- ISSN :
- 19412444 and 01486071
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Journal of Parenteral and Enteral Nutrition
- Accession number :
- edsair.doi.dedup.....e3458a9fdb4f6e4d0eb0fb6204ebd3fb