A two-armed lanthanoid-chelating paramagnetic NMR probe linked to proteins via thioether linkages

Authors :: Wei-Min Liu
Marcellus Ubbink
Anneloes Blok
Simon P. Skinner
Dmitri V. Filippov
Mathias A. S. Hass
Mark Overhand
Monika Timmer
Source :: Chemistry (Weinheim an der Bergstrasse, Germany). 20(21)
Publication Year :: 2014
Abstract: Paramagnetic NMR probes provide valuable long-range structural information on proteins and protein complexes. A new, stable, two-armed lanthanoid probe is reported that can be attached to a protein site-specifically via chemically inert thioether linkages.

Subjects :: Lanthanide
Models, Molecular
Molecular Structure
Organic Chemistry
A protein
General Chemistry
Lanthanoid Series Elements
Catalysis
Paramagnetism
chemistry.chemical_compound
Protein structure
Thioether
chemistry
Polymer chemistry
Posttranslational modification
Organic chemistry
Chelation
Nuclear Magnetic Resonance, Biomolecular
Chelating Agents

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