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A signature pattern of cortical atrophy in dementia with Lewy bodies: A study on 333 patients from the European DLB consortium
- Source :
- Oppedal, K, Ferreira, D, Cavallin, L, Lemstra, A W, ten Kate, M, Padovani, A, Rektorova, I, Bonanni, L, Wahlund, L-O, Engedal, K, Nobili, F, Kramberger, M, Taylor, J-P, Hort, J, Snædal, J, Blanc, F, Walker, Z, Antonini, A, Westman, E, Aarsland, D & Alzheimer's Disease Neuroimaging Initiative 2019, ' A signature pattern of cortical atrophy in dementia with Lewy bodies: A study on 333 patients from the European DLB consortium ', Alzheimer's and Dementia, vol. 15, no. 3, pp. 400-409 . https://doi.org/10.1016/j.jalz.2018.09.011, Aarsland, D 2018, ' A signature pattern of cortical atrophy in dementia with Lewy bodies : a study on 333 patients from The European DLB Consortium ', Alzheimer's & dementia : the journal of the Alzheimer's Association . https://doi.org/10.1016/j.jalz.2018.09.011, Alzheimer's and Dementia, 15(3), 400-409. Elsevier
- Publication Year :
- 2019
-
Abstract
- Introduction: We explored regional brain atrophy patterns and their clinical correlates in dementia with Lewy bodies (DLB). Methods: In this multicentre study, we included a total of 333 patients with DLB, 352 patients with Alzheimer's disease (AD), and 233 normal controls and used medial temporal lobe atrophy, posterior atrophy, and frontal atrophy (GCA-F) visual rating scales. Patients were classified according to four atrophy patterns. Results: Patients with DLB had higher scores on all the three atrophy scales than normal controls but had less medial temporal lobe atrophy than those with AD (all P values
- Subjects :
- Male
0301 basic medicine
Pathology
Epidemiology
Dementia with Lewy bodies
Typical Alzheimer's disease atrophy pattern
0302 clinical medicine
Cerebral Cortex
medicine.diagnostic_test
Health Policy
Alzheimer's disease
Mental Status and Dementia Tests
Minimal-atrophy pattern
Europe
Psychiatry and Mental Health
Medial temporal atrophy
Posterior atrophy frontal atrophy
Female
Differential diagnosis
Lewy Body Disease
medicine.medical_specialty
Hippocampal spearing atrophy pattern
Limbic-predominant atrophy pattern
Neuroimaging
behavioral disciplines and activities
Diagnosis, Differential
03 medical and health sciences
Cellular and Molecular Neuroscience
Atrophy
Magnetic resonance imaging
Developmental Neuroscience
Alzheimer Disease
mental disorders
medicine
Humans
Dementia
Aged
Retrospective Studies
Cortical atrophy
business.industry
Neurology (clinical)
Geriatrics and Gerontology
medicine.disease
nervous system diseases
030104 developmental biology
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 15525260
- Volume :
- 15
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Alzheimer's and Dementia
- Accession number :
- edsair.doi.dedup.....e33efb77679452d2113c42ca2752cd65