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Stimulant and Atypical Antipsychotic Medications For Children Placed in Foster Homes
- Source :
- PLoS ONE, PLoS ONE, Vol 8, Iss 1, p e54152 (2013)
- Publication Year :
- 2013
- Publisher :
- Public Library of Science, 2013.
-
Abstract
- OBJECTIVES: The purpose of this study is to examine the use of prescribed psychoactive medications in a prospective cohort of children shortly after they entered foster homes; and to identify demographics, maltreatment history, psychiatric diagnoses including ADHD comorbidity, and level of aggression that contribute to prescribed use of stimulant and atypical antipsychotic medication over time. METHODS: The sample included N = 252 children (nested in 95 sibling groups) followed for three years up to 4 yearly waves. RESULTS: Nearly all (89%) met criteria for at least one of eight psychiatric diagnoses and 31% (75/252) used one or more prescribed psychoactive medications. Over half (55%) were diagnosed with Attention Deficit Hyperactivity Disorder (ADHD); of these 38% used stimulants and 36% used atypical antipsychotics. Of the 75 medicated children, 19% received ≥3 different classes of drugs over the course of the study. Stimulants (69%) and atypical antipsychotics (65%) were the most frequently used drugs among medicated children. Adjusted odds ratios (AOR) showed that male gender (AOR = 3.2; 95% CI = 1.5-9.3), African American vs Latino ethnicity (AOR = 5.4; 95% CI = 2.1-14.2), ADHD regardless of Oppositional Defiant (ODD) or Conduct (CD) comorbidity (AOR = 6.0, 95% CI = 1.3-27.5), ODD or CD (AOR = 11.1, 95% CI = 2.1-58.6), and Separation Anxiety (AOR = 2.0, 95% CI = 1.0-4.0) psychiatric disorders were associated with the use of prescribed stimulants; while male gender (AOR = 3.8, 95% CI = 1.5-9.3), African American vs Latino (AOR = 5.1, 95% CI = 1.2-9.2) or Mixed/Other ethnicity (AOR = 3.3, 95% CI = 1.9-13.7), ADHD regardless of ODD or CD comorbidity (AOR = 5.8, 95% CI = 1.2-28.7), ODD or CD (AOR = 13.9, 95% CI = 3.3-58.5), Major Depression/Dysthymia (AOR = 2.8, 95% CI = 1.1-6.7) psychiatric disorders, and history of sexual abuse (AOR = 4.6, 95% CI = 1.3-18.4) were associated with the use of prescribed atypical antipsychotics. CONCLUSION: The aggressive use of atypical antipsychotics, which has unknown metabolic risks, suggests that the efficacy and safety of such treatment strategies for psychiatrically ill children in foster care should be monitored. Language: en
- Subjects :
- Male
Pediatrics
Non-Clinical Medicine
Psychopharmacology
medicine.medical_treatment
Poison control
lcsh:Medicine
Comorbidity
Political Aspects of Health
Social Policy
Social and Behavioral Sciences
Foster Home Care
0302 clinical medicine
5. Gender equality
Sociology
Adolescent Psychiatry
Anxiety, Separation
Psychology
Child Abuse
Prospective Studies
Human Families
lcsh:Science
Child
Depression (differential diagnoses)
Applied Psychology
Psychiatry
Child Psychiatry
Multidisciplinary
Child and Adolescent Health Policy
05 social sciences
Child Health
Hispanic or Latino
3. Good health
Mental Health
Child, Preschool
Medicine
Female
Public Health
Social Welfare
050104 developmental & child psychology
Research Article
Antipsychotic Agents
medicine.medical_specialty
Drugs and Devices
Social Psychology
Adolescent
medicine.drug_class
Political Science
Atypical antipsychotic
Psychological Stress
Neuropsychiatric Disorders
Patient Advocacy
Biology
03 medical and health sciences
medicine
Attention deficit hyperactivity disorder
Humans
0501 psychology and cognitive sciences
Behavior
Psychological and Psychosocial Issues
Health Care Policy
lcsh:R
Psychoses
Odds ratio
Drug Policy
medicine.disease
Adjustment (Psychology)
Long-Term Care
030227 psychiatry
Stimulant
Black or African American
Sexual abuse
Attention Deficit Disorder with Hyperactivity
lcsh:Q
Central Nervous System Stimulants
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 8
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....e331b23a68ca19edcad7b9cf7c1c1885