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Childhood multisystem inflammatory syndrome associated with COVID-19 (MIS-C): Distinct from Kawasaki disease or part of the same spectrum?
- Source :
- Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. 33
- Publication Year :
- 2021
-
Abstract
- One of the most challenging and intriguing phenomena observed during the COVID-19 pandemic has been the multisystem inflammatory syndrome in children (MIS-C). Patients with this condition present with some clinical features similar to those of Kawasaki disease (KD) and display signs and symptoms that are uncommon or rarely occur in this disorder, such as gastrointestinal complaints and myocarditis, often leading to myocardial failure and shock. In addition, patients' age is older than that of children with classic KD. Management is based on administering intravenous immunoglobulin, glucocorticoids, and anakinra in the most severe instances. It is still debated whether MIS-C and KD are different illnesses or represent a disease continuum.
- Subjects :
- multisystem inflammatory syndrome
SARS-CoV-2
Immunology
COVID-19
Mucocutaneous Lymph Node Syndrome
Systemic Inflammatory Response Syndrome
toxic shock syndrome
children
Pediatrics, Perinatology and Child Health
Immunology and Allergy
Humans
kawasaki disease
macrophage activation syndrome
Child
Pandemics
Subjects
Details
- ISSN :
- 13993038
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
- Accession number :
- edsair.doi.dedup.....e32a5dceee2c25aec842b48ac01ec6b1