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'Salt and Pepper Endothelium' Recurring After Descemet Membrane Endothelial Keratoplasty
- Source :
- Cornea. 35(5)
- Publication Year :
- 2016
-
Abstract
- PURPOSE To describe the presence of "salt and pepper endothelium", that is, typical cellular inclusion bodies in a patient with Fuchs endothelial corneal dystrophy (FECD), that recurred in the donor corneal endothelial cells after Descemet membrane endothelial keratoplasty (DMEK). METHODS A 76-year-old man underwent DMEK for FECD in his left eye. Routine specular microscopy imaging, best-corrected visual acuity measurements, and pachymetry measurements were performed before and after surgery. RESULTS Besides large guttae indicating FECD, preoperative specular microscopy images showed variable-sized dark cellular inclusion bodies in the endothelial cells. One month after DMEK, donor endothelial cells appeared normal; however, at 3 months, the typical inclusion bodies reappeared and progressed slowly within a 4-year follow-up period. Both best-corrected visual acuity and pachymetry were stable throughout the study period. CONCLUSIONS "Salt and pepper endothelium" recurred after the host tissue was exchanged by donor Descemet membrane, that is, a DMEK graft. These changes may indicate that either the donor corneal endothelial cell morphology is modified by adjacent tissue structures or that it is completely replaced by recipient endothelium within the first months after surgery.
- Subjects :
- Male
medicine.medical_specialty
Visual acuity
genetic structures
Descemet membrane
Endothelium
Corneal Pachymetry
Fuchs Endothelial Dystrophy
Cell Count
Inclusion bodies
03 medical and health sciences
0302 clinical medicine
Recurrence
Ophthalmology
Pepper
medicine
Humans
Corneal pachymetry
Aged
Inclusion Bodies
medicine.diagnostic_test
business.industry
Endothelium, Corneal
Fuchs' Endothelial Dystrophy
Middle Aged
eye diseases
Tissue Donors
medicine.anatomical_structure
Descemet Stripping Endothelial Keratoplasty
030221 ophthalmology & optometry
Female
sense organs
medicine.symptom
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15364798
- Volume :
- 35
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Cornea
- Accession number :
- edsair.doi.dedup.....e30bb18d7f288b6d6ecbaa68d24837e3