Back to Search
Start Over
Common Genetic Variants Explain the Majority of the Correlation Between Height and Intelligence: The Generation Scotland Study
- Source :
- Behavior Genetics, 2014, ' Common genetic variants explain the majority of the correlation between height and intelligence : the generation Scotland study ', Behavior Genetics, vol. 44, no. 2, pp. 91-96 . https://doi.org/10.1007/s10519-014-9644-z
- Publication Year :
- 2014
- Publisher :
- Springer Science and Business Media LLC, 2014.
-
Abstract
- Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49–63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences. Electronic supplementary material The online version of this article (doi:10.1007/s10519-014-9644-z) contains supplementary material, which is available to authorized users.
- Subjects :
- Adult
Male
Height and intelligence
Genetic correlation
Genotype
SAMPLES
Intelligence
CHILDHOOD
Bivariate analysis
Biology
DISEASE
Cohort Studies
Correlation
03 medical and health sciences
0302 clinical medicine
Genetic variation
Genetics
Humans
COHORT
Genetics(clinical)
Molecular genetics
METAANALYSIS
Genetics (clinical)
Ecology, Evolution, Behavior and Systematics
Original Research
Aged
Oligonucleotide Array Sequence Analysis
030304 developmental biology
0303 health sciences
HERITABILITY
Height
Genetic Variation
ASSOCIATION
Middle Aged
Heritability
SCOTTISH FAMILY HEALTH
Body Height
Phenotype
Scotland
Cohort
PLEIOTROPY
Female
Generation Scotland
030217 neurology & neurosurgery
Cohort study
Demography
Subjects
Details
- ISSN :
- 15733297 and 00018244
- Volume :
- 44
- Database :
- OpenAIRE
- Journal :
- Behavior Genetics
- Accession number :
- edsair.doi.dedup.....e2dfb0581c8dc8e2745ff8cd78b3f2f0
- Full Text :
- https://doi.org/10.1007/s10519-014-9644-z