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Common Genetic Variants Explain the Majority of the Correlation Between Height and Intelligence: The Generation Scotland Study

Authors :
Peter M. Visscher
Archie Campbell
Riccardo E. Marioni
Generation Scotland
David J. Porteous
Shona M. Kerr
Lynne J. Hocking
Ian J. Deary
G. David Batty
Caroline Hayward
Source :
Behavior Genetics, 2014, ' Common genetic variants explain the majority of the correlation between height and intelligence : the generation Scotland study ', Behavior Genetics, vol. 44, no. 2, pp. 91-96 . https://doi.org/10.1007/s10519-014-9644-z
Publication Year :
2014
Publisher :
Springer Science and Business Media LLC, 2014.

Abstract

Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49–63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences. Electronic supplementary material The online version of this article (doi:10.1007/s10519-014-9644-z) contains supplementary material, which is available to authorized users.

Details

ISSN :
15733297 and 00018244
Volume :
44
Database :
OpenAIRE
Journal :
Behavior Genetics
Accession number :
edsair.doi.dedup.....e2dfb0581c8dc8e2745ff8cd78b3f2f0
Full Text :
https://doi.org/10.1007/s10519-014-9644-z