Back to Search Start Over

Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs

Authors :
Sabine H. van Rijt
Peter J. Sadler
Source :
Drug discovery today. 14(23-24)
Publication Year :
2009

Abstract

This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging. Current research addressing the problems associated with platinum drugs has focused on other metal-based therapeutics that have different modes of action and on prodrug and targeting strategies in an effort to diminish the side-effects of cisplatin chemotherapy.

Details

ISSN :
18785832 and 13596446
Volume :
14
Issue :
23-24
Database :
OpenAIRE
Journal :
Drug discovery today
Accession number :
edsair.doi.dedup.....e2ca25bd0e92475a2cf8e8128e27f58e