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Effects of bilateral prefrontal rTMS on brain activation during social - emotional evaluation in schizophrenia: A double-blind, randomized, exploratory study
- Source :
- Schizophrenia Research, 202, 210-211. ELSEVIER SCIENCE BV
- Publication Year :
- 2018
-
Abstract
- This exploratory study reports on the effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on (prefrontal) brain activity changes during ambiguous emotional evaluation in patients with schizophrenia. Before and after randomly assigned treatment with active and sham rTMS, patients performed the Wall of Faces task during fMRI scanning. fMRI analysis showed that rTMS treatment resulted in reduced activation of striato-fronto-parietal brain areas, while activation increased compared to baseline after sham. Thus, prefrontal rIMS may normalize an increased brain response to ambiguous emotional stimuli, but future studies should confirm these findings. (C) 2018 Elsevier B.V. All rights reserved.
- Subjects :
- Adult
Male
Brain activation
medicine.medical_specialty
TRANSCRANIAL MAGNETIC STIMULATION
Brain activity and meditation
medicine.medical_treatment
Emotions
Exploratory research
Audiology
behavioral disciplines and activities
050105 experimental psychology
Double blind
03 medical and health sciences
0302 clinical medicine
WORKING-MEMORY
Double-Blind Method
Social-emotional
mental disorders
rTMS
Social emotional learning
medicine
Humans
0501 psychology and cognitive sciences
Biological Psychiatry
Brain Mapping
business.industry
Working memory
musculoskeletal, neural, and ocular physiology
05 social sciences
fMRI
Brain
medicine.disease
Magnetic Resonance Imaging
Transcranial magnetic stimulation
Psychiatry and Mental health
Treatment Outcome
Social Perception
nervous system
Schizophrenia
Female
Schizophrenic Psychology
Negative symptoms
business
030217 neurology & neurosurgery
psychological phenomena and processes
Subjects
Details
- Language :
- English
- ISSN :
- 09209964
- Database :
- OpenAIRE
- Journal :
- Schizophrenia Research, 202, 210-211. ELSEVIER SCIENCE BV
- Accession number :
- edsair.doi.dedup.....e2c2c5f5a2561c38103301a45a92bf86